Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus. Celecoxib does not prevent the progression of either type of arthritis. Celecoxib is used to reduce pain and inflammation in osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis. This drug may rarely cause serious liver disease. Ask your doctor, nurse, or pharmacist any questions you may have about this medicine. Ask your doctor, nurse, or pharmacist any questions you may have about this medicine. Celebrex works by blocking the action of a substance in the body by inhibiting the breakdown of Celecoxib in the liver. In the body called cyclo-oxygenase. Celecoxib differs from other NSAIDs in that it causes less inflammation and ulceration of the stomach and intestine and does not interfere with the clotting of blood.
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