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Lexapro is used to treat anxiety and major depressive disorder. People take for granted. Because Escitalopram appears to work by increasing the available supply of serotonin, a chemical messenger in the brain believed to influence mood. Lexapro affects chemicals in the brain, is an important factor in the development and severity of depressive symptoms, such as sad mood, fatigue, lack of pleasure, etc. Lexapro is actually an updated version of an older anti-depressant called Celexa. Lexapro works by increasing the available supply of serotonin, a chemical messenger in the brain that helps maintain mental balance. Lexapro anti depressant has helped millions and is continuing to help millions. Lexapro works by increasing the available supply of serotonin. Lexapro affects chemicals in the brain that helps maintain mental balance.